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Peg-12 Dimethicone: Safety Measures/Side Effects

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PEG 12 polydimethylsiloxane is a kind of PEG combined with polydimethylsiloxane (polydimethylsiloxane), polydimethylsiloxane is a silicone-based polymer, Give the formula smooth, promote spreadability and increase lubricity. It can be used as a surface tension inhibitor, hair conditioner, skin conditioner, wetting agent, emulsifier and foaming agent (source) in a variety of beauty products and cosmetics. Due to the low molecular weight of PEG 12 dimethicone, skin absorption is minimal.


PEG 12 polydimethylsiloxane is a kind of PEG combined with polydimethylsiloxane (polydimethylsiloxane), polydimethylsiloxane is a silicone-based polymer, Give the formula smooth, promote spreadability and increase lubricity. It can be used as a surface tension inhibitor, hair conditioner, skin conditioner, wetting agent, emulsifier and foaming agent (source) in a variety of beauty products and cosmetics. Due to the low molecular weight of PEG 12 dimethicone, skin absorption is minimal.

Although there are many concerns about PEG, due to their different characteristics, they are regarded as an ingredient in many products. A study published in the Journal of Toxicology in 2005 entitled "Safety Assessment of Polyethylene Glycol (PEG) and Its Derivatives Used in Cosmetics" concluded that: "Considering all relevant aspects of this compound Information is available, and the safety of these endpoints cannot be determined based on the mode of action and mechanism of action. Therefore, the conclusions drawn from existing data are that PEG and its ether (lauryl) bases with a wide molecular weight range (more than 200 to 10,000) , Cetyl, cetearyl stearate, stearate and fat) and fatty acid esters (laurate, dilaurate, stearate, stearate) can be used safely In cosmetics."

PEG 12 dimethicone is not considered an irritant or sensitizer. It has been approved for skin use by CIR and FDA, but it cannot be used for damaged skin.

Safety measures/side effects:

The cosmetics database found that PEG 12 dimethicone has moderate hazards (depending on usage), and pay attention to pollution and toxicity issues.

According to a study published in the International Journal of Toxicology, PEG (including PEG 12 Dimethicone) may contain harmful impurities, including: ethylene oxide, based on experimental results, it is known to increase uterine and breast cancer, The National Toxicology Program reports the incidence of leukemia and brain cancer; 1,4-dioxane, a known carcinogen; PAHs, known to increase the risk of breast cancer; lead; iron; and arsenic (source ).

Products and preparations containing PEG must not be used on damaged or irritated skin. Although it is believed that PEG is safe for topical use on healthy skin, studies have shown that patients with severe burns have been treated with PEG-based antibacterial cream. This treatment can cause kidney toxicity. "It was determined that the PEG content in the antimicrobial cream was the cause. However, in the skin integrity study, there was no evidence of systemic toxicity. Due to the observed kidney effects of burn patients, the CIR expert team determined their conclusions. The PEG component Sex Safety, indicating that cosmetics containing these ingredients cannot be used on damaged skin."


Hangzhou Silva New Material Technology Co., Ltd . is a professional China manufacturer and supplier of    PEG-12 Dimethicone   and   1,3,5,7-Tetramethylcyclotetrasiloxane  . Welcome to consult and order: https://www.silways.com/application/personal-care/peg-12-dimethicone-silway593.html

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